Profile

Organix

Urine
28 ±5 days Days

Indications


  • Fatigue or low energy: Tiredness, reduced stamina or feeling easily depleted.
  • Mood or cognitive changes: Low mood, anxiety, irritability, poor focus or memory issues.
  • Chronic stress symptoms: Feeling overwhelmed, burnt out or struggling to cope with daily demands.
  • Digestive discomfort: Bloating, gas, irregular bowel habits or suspected gut imbalance.
  • Unexplained aches or pain: Ongoing muscle discomfort or physical tension without a clear cause.
  • Inflammation-related concerns: Generalised swelling, stiffness or sensitivity.
  • Sleep disturbances: Difficulty falling asleep, disrupted sleep or waking unrefreshed.
  • Skin concerns: Intermittent irritation, breakouts or skin changes linked with stress or diet.
  • Weight changes: Unexplained weight gain, difficulty losing weight or fluctuating weight patterns.
  • Behaviour or focus issues: Inattention, restlessness or behavioural changes in children or adults.

Overview

The Organix Test offers a detailed examination of various organic acids present in a urine sample, covering multiple metabolic processes. This includes assessment of markers related to nutrient utilisation, microbial interactions, energy production, and detoxification pathways. By analysing a wide range of biochemical indicators, it provides insights into overall metabolic activity and nutritional balance. The comprehensive nature of the test allows for a broad perspective on bodily functions without focusing on specific health conditions.

This urine analysis is designed for individuals interested in gaining deeper understanding of their metabolism, digestive function, or nutrient status. It evaluates metabolites linked to gut microbiota activity, mitochondrial performance, vitamin metabolism, antioxidant levels, and the body’s ability to manage environmental exposures. Such broad metabolic profiling can support lifestyle choices and personal wellbeing optimisation, highlighting areas where biochemical processes may benefit from targeted attention or adjustment.

Organix delivers a structured overview of functional metabolism, helping users appreciate the complexity of their biochemical balance. The range of markers included provides valuable context for those aiming to explore connections between diet, metabolism, and general health. This test supports informed conversations around wellness and metabolic function, making it a useful tool for personal health awareness and research purposes.

Organix is intended for informational, educational, wellness and/or research purposes only. It is not intended for use in medical diagnosis, disease screening or clinical decision-making. Organix is not a replacement for clinical laboratory testing and does not provide medical diagnoses. This content is intended for general information within the EU market and should not be interpreted as a regulated in-vitro diagnostic claim.

Videos

Quick introduction video

Downloads

Brochure
English
Collection instructions
Danish
English
Hebrew
Sample Report
English

Research

Downloadable research


Noninvasive urinary organic acids test to assess biochemical and nutritional individuality in autistic children

 

Research:

  1. Katuzna-Czaplinska J. Noninvasive urinary organic acids test to assess biochemical and nutritional individuality in autistic children. Clin Biochem. 2011;44(8-9):686-691. https://www.ncbi.nlm.nih.gov/pubmed/21300048
  2. Broquist HP, Luhby AL. Detection and isolation of formiminoglutamic acid from urine in folic acid deficiency in humans. Proc Soc Exp Biol Med. 1959;100(2):349-354. https://journals.sagepub.com/doi/abs/10.3181/00379727-100-24623
  3. Sun A-l, Ni Y-h, Li X-b, et al. Urinary methylmalonic acid as an indicator of early vitamin B12 deficiency and its role in polyneuropathy in type 2 diabetes. J Diabetes Res. 2014;2014. https://www.hindawi.com/journals/jdr/2014/921616/
  4. Kwok T, Cheng G, Lai W, Poon P, Woo J, Pang C. Use of fasting urinary methylmalonic acid to screen for metabolic vitamin B12 deficiency in older persons. Nutrition. 2004;20(9):764-768.https://www.ncbi.nlm.nih.gov/pubmed/15325684
  5. Brown R, Thornton MJ, Price J. The effect of vitamin supplementation on the urinary excretion of tryptophan metabolites by pregnant women. J Clin Invest. 1961;40(4):617-623. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC290765/
  6. Lykouras L, Markianos M, Hatzimanolis J, Malliaras D, Stefanis C. Association of biogenic amine metabolites with symptomatology in delusional (psychotic) and nondelusional depressed patients. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1995;19(5):877-887. https://www.ncbi.nlm.nih.gov/pubmed/8539425
  7. Frankenhaeuser M, Lundberg U, Von Wright MR, Von Wright J, Sedvall G. Urinary monoamine metabolites as indices of mental stress in healthy males and females. Pharmacol Biochem Behav. 1986;24(6):1521-1525. https://www.ncbi.nlm.nih.gov/pubmed/8539425
  8. Mitochondrial Medicine Society's Committee on D, Haas RH, Parikh S, et al. The in-depth evaluation of suspected mitochondrial disease. Mol Genet Metab. 2008;94(1):16-37. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810849/
  9. Dimmock DP, Lawlor MW. Presentation and Diagnostic Evaluation of Mitochondrial Disease. Pediatr Clin North Am. 2017;64(1):161-171. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130109/
  10. Wu H, Jiang K, Gu G, Wu Y, Yu S. [The relationship of occupational stress and the level of some hormone metabolites in urine]. Chinese J Indust Hyg Occup Dis. 2014;32(2):83-86. https://www.ncbi.nlm.nih.gov/pubmed/24630003
  11. Jeon SW, Kim Y-K. Inflammation-induced depression: Its pathophysiology and therapeutic implications. J Neuroimmunol. 2017;313:92-98. https://www.ncbi.nlm.nih.gov/pubmed/29153615
  12. Hryhorczuk LM, Novak EA, Gershon S. Gut flora and urinary phenylacetic acid. Science. 1984;226(4677):996. https://science.sciencemag.org/content/226/4677/996.1
  13. Mora Brugues J, Gonzalez Sastre F. Influence of intestinal flora on the elimination of phenylacetic acid in urine. Clinical Chem. 1986;32(1 Pt 1):223. ttps://academic.oup.com/clinchem/article-abstract/32/1/223/5652268?redirectedFrom=fulltexth
  14. Del Rio D, Stalmach A, Calani L, Crozier A. Bioavailability of Coffee Chlorogenic Acids and Green Tea Flavan-3-ols. Nutrients. 2010;2(8):820. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257704/
  15. Pieczenik SR, Neustadt J. Mitochondrial dysfunction and molecular pathways of disease. Exp Mol Path. 2007;83(1):84-92. https://www.ncbi.nlm.nih.gov/pubmed/17239370
  16. Caito SW, Aschner M. Mitochondrial Redox Dysfunction and Environmental Exposures. Antioxid Redox Signal. 2015;23(6):578-595. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4544749/
  17. Depeint F, Bruce WR, Shangari N, Mehta R, O'Brien PJ. Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. Chem Biol Interact. 2006;163(1-2):94-112. https://www.ncbi.nlm.nih.gov/pubmed/16765926"
  18. Wojtczak L, Slyshenkov VS. Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals--the role of glutathione. BioFactors. 2003;17(1-4):61-73. https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/biof.5520170107
  19. Tsoukalas D, Alegakis A, Fragkiadaki P, et al. Application of metabolomics: Focus on the quantification of organic acids in healthy adults. Int J Mol Med. 2017;40(1):112-120. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466383/
  20. Astarita G, Langridge J. An emerging role for metabolomics in nutrition science. J Nutrigenet Nutrigenom. 2013;6(4-5):181-200. https://www.karger.com/Article/FullText/354403"
  21. Anderson NM, Mucka P, Kern JG, Feng H. The emerging role and targetability of the TCA cycle in cancer metabolism. Protein Cell. 2017. https://link.springer.com/article/10.1007/s13238-017-0451-1
  22. Cardaci S, Ciriolo MR. TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State. Int J Cell Biol. 2012;2012:161837. https://www.hindawi.com/journals/ijcb/2012/161837/
  23. . Rojczyk-Golebiewska E, Kucharzewski M. Influence of chosen metals on the citric acid cycle. Pol Merkur Lekarski. 2013;34(201):175-178. https://www.ncbi.nlm.nih.gov/pubmed/23700830
  24. Strydom CRC. The effect of selected metals on the central metabolic pathways in biology: A review. Water SA. 2006. https://www.ajol.info/index.php/wsa/article/view/5155
  25. Nicolson GL. Mitochondrial dysfunction and chronic disease: treatment with natural supplements. Alt Therap Health Med. 2014;20 Suppl 1:18-25. http://www.alternative-therapies.com/index.cfm/fuseaction/Content.Main/id/72/E-pubAheadofPrint

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