GI MAP
Stool
21 days +/- 4 Days
Indications
- Digestive symptoms: Chronic diarrhoea, constipation, bloating, gas or abdominal pain.
- Altered bowel habits: Ongoing changes in stool frequency, urgency or consistency.
- Suspected gastrointestinal disorders: Evaluation in contexts such as irritable bowel syndrome, inflammatory bowel disease or coeliac disease.
- Recurrent gastrointestinal symptoms: Exploration of potential bacterial contributors including Escherichia coli or Helicobacter pylori.
- Malabsorption concerns: Unexplained weight loss, anaemia or signs of nutrient insufficiency.
- Immune-related conditions: Investigation of gastrointestinal factors in autoimmune or inflammatory presentations.
- Skin conditions: Eczema, acne or psoriasis where gut involvement is considered.
- Fatigue or neurological symptoms: Brain fog, low energy or mood changes in complex clinical presentations.
Overview
The Gastrointestinal Microbial Profile (GI-MAP) provides an exploratory overview of the gut environment using advanced molecular techniques. By applying quantitative PCR (qPCR) to a single stool sample, the analysis offers insights into the composition and balance of microorganisms present within the digestive system. This test is designed to give practitioners an overview of patterns related to gastrointestinal health, including microbial balance, digestive function, and general markers that may support discussions around gut-related wellbeing.
Videos
Quick introduction video
Research
- Abubakar I, Irvine L, Aldus CF, et al. A systematic review of the clinical, public health and costeffectiveness of rapid diagnostic tests for the detection and identification of bacterial intestinal pathogens in faeces and food. Health Technol Assess. 2007;11(36):1-216.
- Amar CF, East CL, Gray J, Iturriza-Gomara M, Maclure EA, McLauchlin J. Detection by PCR of Eight groups of enteric pathogens in 4,627 faecal samples: re-examination of the English casecontrol Infectious Intestinal Disease Study (1993-1996). Eur J Clin Microbiol Infect Dis. 2007;26(5):311-323.
- Bischoff SC, Barbara G, Buurman W, et al. Intestinal permeability — a new target for disease prevention and therapy. BMC gastroenterology. 2014;14:189.
- Canny GO, McCormick BA. Bacteria in the intestine, helpful residents or enemies from within? Infection and immunity. 2008;76(8):3360-3373.
- Fasano A, Shea-Donohue T. Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases. Nature clinical practice. 2005;2(9):416-422.
- Iijima Y, Asako NT, Aihara M, Hayashi K. Improvement in the detection rate of diarrhoeagenic Bacteria in human stool specimens by a rapid real-time PCR assay. Journal of medical microbiology. 2004;53(Pt 7):617-622.
- Kahlau P, Malecki M, Schildgen V, et al. Utility of two novel multiplexing assays for the detection of gastrointestinal pathogens - a first experience. SpringerPlus. 2013;2(1):106.
- Kamada N, Seo SU, Chen GY, Nunez G. Role of the gut microbiota in immunity and inflammatory disease. Nature reviews. Immunology. 2013;13(5):321-335.
- Khanna S, Tosh PK. A clinician's primer on the role of the microbiome in human health and disease. Mayo Clinic proceedings. 2014;89(1):107-114.
- Othman M, Aguero R, Lin HC. Alterations in intestinal microbial flora and human disease. Current opinion in gastroenterology. 2008;24(1):11-16.
- Rashid T, Ebringer A. Autoimmunity in Rheumatic Diseases Is Induced by Microbial Infections via Crossreactivity or Molecular Mimicry. Autoimmune diseases. 2012;2012:539282.
- Schabereiter-Gurtner C, Hirschl AM, Dragosics B, et al. Novel real-time PCR assay for detection of Helicobacter pylori infection and simultaneous clarithromycin susceptibility testing of stool and biopsy specimens. Journal of clinical microbiology. 2004;42(10):4512-4518.
- Stecher B, Hardt WD. The role of microbiota in infectious disease.Trends in microbiology. 2008;16(3):107-114.
- Tiwana H, Wilson C, Walmsley RS, et al. Antibody responses to gut bacteria in ankylosing spondylitis, rheumatoid arthritis, Crohn's disease and ulcerative colitis. Rheumatology international. 1997;17(1):11-16.
See also Brochure under ‘Downloadable files’ for even more research.
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Simply Nature Ltd
11 Old Factory Buildings Battenhurst Road
Stonegate East Sussex TN5 7DU,
United Kingdom
Stonegate East Sussex TN5 7DU,
United Kingdom